Cytokines Studied in Carp (Cyprinus carpio L.) in Response to Important Diseases

Autor: Ali Asghar Baloch, Ehdaa Eltayeb Eltigani Abdelsalam, Veronika Piačková
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Fishes, Vol 7, Iss 1, p 3 (2021)
Druh dokumentu: article
ISSN: 2410-3888
DOI: 10.3390/fishes7010003
Popis: Cytokines belong to the most widely studied group of intracellular molecules involved in the function of the immune system. Their secretion is induced by various infectious stimuli. Cytokine release by host cells has been extensively used as a powerful tool for studying immune reactions in the early stages of viral and bacterial infections. Recently, research attention has shifted to the investigation of cytokine responses using mRNA expression, an essential mechanism related to pathogenic and nonpathogenic-immune stimulants in fish. This review represents the current knowledge of cytokine responses to infectious diseases in the common carp (Cyprinus carpio L.). Given the paucity of literature on cytokine responses to many infections in carp, only select viral diseases, such as koi herpesvirus disease (KHVD), spring viremia of carp (SVC), and carp edema virus disease (CEVD), are discussed. Aeromonas hydrophila is one of the most studied bacterial pathogens associated with cytokine responses in common carp. Therefore, the cytokine-based immunoreactivity raised by this specific bacterial pathogen is also highlighted in this review.
Databáze: Directory of Open Access Journals
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