The relationship between aspirin consumption and hepatocellular carcinoma: a systematic review and meta-analysis

Autor: Shuai Wang, Lijuan Zuo, Zhaojin Lin, Zhiqin Yang, Ran Chen, Yan Xu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: European Journal of Medical Research, Vol 28, Iss 1, Pp 1-14 (2023)
Druh dokumentu: article
ISSN: 2047-783X
DOI: 10.1186/s40001-023-01204-5
Popis: Abstract Background Recent studies have shown that aspirin consumption may reduce the risk of hepatocellular carcinoma (HCC), but their correlation is still not fully understood. This meta-analysis aimed to investigate the correlation between aspirin consumption and HCC. Methods A systematic literature search was conducted on PubMed, Scopus, Cochrane Library, EMBASE, and Web of Science databases. The search period was from the establishment of the database to July 1, 2022 with no language restrictions. Results A total of 19 studies including three prospective studies and 16 retrospective ones with 2,217,712 patients were included. Compared with those who did not take aspirin, those who took aspirin had a 30% lower risk of HCC (hazard ratio [HR] = 0.70, 95% confidence interval [CI] 0.63–0.76, I 2 = 84.7%, P
Databáze: Directory of Open Access Journals
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