A diencephalic circuit in rats for opioid analgesia but not positive reinforcement

Autor: Maggie W. Waung, Kayla A. Maanum, Thomas J. Cirino, Joseph R. Driscoll, Chris O’Brien, Svetlana Bryant, Kasra A. Mansourian, Marisela Morales, David J. Barker, Elyssa B. Margolis
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-28332-6
Popis: Opioids are potent analgesics but also have addiction risk. Here a lateral preoptic area to lateral habenula connection is identified by which opioids relieve ongoing pain but do not produce reward in animals that do not have ongoing pain.
Databáze: Directory of Open Access Journals