Postoperative atypical hemolytic uremic syndrome in nontransplant setting: A case report with review of literature

Autor: Anil Khetarpal, Vidhi Gupta, Urvershi Kotwal
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Global Journal of Transfusion Medicine, Vol 3, Iss 1, Pp 64-67 (2018)
Druh dokumentu: article
ISSN: 2468-8398
2455-8893
DOI: 10.4103/GJTM.GJTM_61_17
Popis: Atypical hemolytic uremic syndrome (aHUS) is a clinical diagnosis characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. Postoperative aHUS in nontransplant patients is a rare entity. The proposed underlying mechanism is complement cascade dysregulation. aHUS has high morbidity and mortality. Prompt intervention with early initiation of therapeutic plasma exchange helps in the hematological remission thus reducing morbidity.
Databáze: Directory of Open Access Journals