Autor: |
Gautam Srivastava, Meng S. Choy, Nicolas Bolik-Coulon, Rebecca Page, Wolfgang Peti |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-023-37372-5 |
Popis: |
Protein phosphatase 1 (PP1) is regulated by intrinsically disordered proteins like inhibitor-3, I3. The authors show that I3 does not inhibit PP1 by forming a rigid complex but instead by binding dynamically with its active site metals, showing how flexibility is used in biology. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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