Oxidative stress, histopathological and genotoxicity of copper oxide nanoparticles in Biomphalaria alexandrina snail

Autor:	Mona Fathi Fol, Fathi A. Abdel-Ghaffar, Hassan Abdel-Malek Hassan, Amina Mohamed Ibrahim
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Biomphalaria alexandrina CuO NPs Histopathology RAPD Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-74439-9
Popis:	Abstract Higher usage of copper oxide nanomaterials in industrial and biomedical fields may cause an increase of these nanoparticles in aquatic environments, which could have a detrimental ecological effect. Thus, the objective of this study was to evaluate the acute toxicity of copper oxide nanoparticles on the freshwater gastropod, Biomphalaria alexandrina. Transmission electron microscopy, x-ray diffraction analysis and UV–VIS spectrophotometer of CuO NPs revealed a typical TEM image and a single crystal structure with average crystallite size of approximately 40 nm also, a sharp absorption band was appeared. Following exposure to sub-lethal concentrations of CuO NPs (LC10, 15.6 mg/l and LC25, 27.2 mg/l), treated snails revealed a significant decrease (p
Databáze:	Directory of Open Access Journals
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