Real-World Experience of Treating Young Adult Patients with Breast Cancer from a Single Center in Southern India
| Autor: | Priya Iyer, Venkatraman Radhakrishnan, Arvind Krishnamurthy, Manikandan Dhanushkodi, Sridevi V., Balasubramanian Ananthi, Ganeshraja Selvaluxmy |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | South Asian Journal of Cancer, Vol 11, Iss 02, Pp 105-111 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2278-330X 2278-4306 |
| DOI: | 10.1055/s-0041-1735481 |
| Popis: | Abstract Priya Iyer Background Breast cancer in young adults is rare and accounts for 5 to 6% of all cancers in this age group. We conducted the present study to look at the demographic features, clinical presentation, and outcomes in this group of patients treated at our center. Patients and Methods The study included breast cancer patients between the age of 15 and 30 years treated at our institute from January 2009 to December 2016. Data were analyzed retrospectively from case records. Event-free survival (EFS) and overall survival (OS) were calculated using the Kaplan–Meier method. Results Young adult breast cancers were reported in 145 out of 6,000 patients (2.41%) diagnosed with breast cancer in the study period. The median age of the patients was 29 years (range: 21–30 years). Stage I, II, III, and IV was observed in 3.4, 33.7, 46.2, and 16.5% of patients, respectively. The median follow-up was 45 months (range: 1.7–128.1 months). The 5-year EFS and OS for stage I, II, III, and IV was 100, 74.5, 47.9, and 0% and 100, 90.8, 55.1, and 0%, respectively. On univariate analysis, stage of the disease and pregnancy-associated breast cancers were found to have a significant association with decreased EFS and OS (p |
| Databáze: | Directory of Open Access Journals |
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