Investigating the Level of Lung Involvement by CT scans in Covid-19 Patients and its Relationship with the Level of Blood Biomarkers: A Retrospective Study
| Autor: | hamidreza asaeian, Farzaneh shoja shafiee, Bahareh Aghajani, Bahareh lashtoo Aghaee |
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| Jazyk: | English<br />Persian |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Mazandaran University of Medical Sciences, Vol 33, Iss 227, Pp 153-158 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1735-9260 1735-9279 |
| Popis: | Background and purpose: Coronavirus disease 2019 (COVID-19) is a multi-organ illness characterized by significant involvement of the coagulation cascade, immune response, and inflammation. This investigation aimed to explore the significance of various biomarkers, such as interleukin 6 (IL-6), lactate dehydrogenase (LDH), D-dimer, and N-terminal prohormone of brain natriuretic peptide (NT-proBNP), concerning lung complications in COVID-19 patients. Materials and methods: This retrospective study was conducted at Imam-Sajjad Hospital in Ramsar, Mazandaran, from May to August 2021 and focused on all COVID-19 patients with lung involvement who were admitted. An experienced radiologist assessed each patient's computed tomography (CT) scans and assigned a lung involvement score ranging from zero to 10 for each lung. These scores were categorized as mild (0-10), moderate (10-15), or severe (15-20). In addition to demographic data, serum levels of IL-6, LDH, D-dimer, and NT-proBNP were obtained from patient records, and all the achieved data were statistically analyzed. Results: A total of 154 patients were included. The distribution across mild (27.3%), moderate (33.7%), and severe (39%) lung involvement in COVID-19 was observed. Notably, levels of IL-6 (P=0.002), D-dimer (P=0.035), and LDH (P |
| Databáze: | Directory of Open Access Journals |
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