Autor: |
Wael Fathy, Mona Hussein, Rehab Magdy, Hatem Elmoutaz, Neveen A Youssef, Marwa F Abd Alla, Ahmed M El Shaarawy, Mohamed Abdelbadie |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-8 (2024) |
Druh dokumentu: |
article |
ISSN: |
1471-2253 |
DOI: |
10.1186/s12871-024-02527-4 |
Popis: |
Abstract Background This work aimed to analyze serum S100B levels and brain-derived neurotrophic factor (BDNF) in patients with lumbar disc prolapse to test their predictive values concerning the therapeutic efficacy of pulsed radiofrequency. Methods This prospective interventional study was carried out on 50 patients candidates for radiofrequency for treating symptomatic lumbar disc prolapse. Pain severity and functional disability were assessed using the Numeric Rating Scale (NRS) and Functional rating index (FRI) before as well as two weeks, 1, 3, and 6 months after the radiofrequency. Quantitative assessment of serum S100B level and BDNF was done for all the included patients one day before radiofrequency. Results The scores of NRS and FRI were significantly improved at two weeks, 1, 3, and 6 months following radiofrequency (P-value |
Databáze: |
Directory of Open Access Journals |
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