Thyroid Autoimmunity in the Context of Type 2 Diabetes Mellitus: Implications for Vitamin D

Autor: Konstantinos Toulis, Xanthippi Tsekmekidou, Evangelos Potolidis, Triantafyllos Didangelos, Anna Gotzamani-Psarrakou, Pantelis Zebekakis, Michael Daniilidis, John Yovos, Kalliopi Kotsa
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: International Journal of Endocrinology, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 1687-8337
1687-8345
DOI: 10.1155/2015/710363
Popis: Vitamin D deficiency has been associated with both type 2 diabetes mellitus (T2DM) and autoimmune disorders. The association of vitamin D with T2DM and thyroid autoimmunity (TAI) has not been investigated. Thus, we aimed to explore the putative association between T2DM and thyroid autoimmunity (TAI) focusing on the role of 25-hydroxy-vitamin D (25(OH)D). Study population included 264 T2DM patients and 234 controls. To explore the potential association between 25(OH)D and thyroid autoimmunity while controlling for potential confounders—namely, age, gender, body mass index, and presence of T2DM—multivariate logistic regression analyses were undertaken. Patients with T2DM were younger (P
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