| Autor: |
Belinelo Valdenir J., Reis Genuína T., Stefani Guglielmo M., Ferreira-Alves Dalton L., Piló-Veloso Dorila |
| Jazyk: |
angličtina |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Journal of the Brazilian Chemical Society, Vol 13, Iss 6, Pp 830-837 (2002) |
| Druh dokumentu: |
article |
| ISSN: |
0103-5053 |
| Popis: |
The furanditerpene 6alpha,7beta-dihydroxyvouacapan-17beta-oic acid (ADV, 1), isolated from Pterodon polygalaeflorus Benth fruits, presents analgesic activity in current rodent experimental models. With the aim to gather data for biological studies it were obtained six new amide derivatives substituted in the furan ring with alkylamine groups, prepared by the Mannich reaction with preformed iminium salts. These derivatives were evaluated in a preliminary in vitro pharmacological test. Structures were determined by spectroscopic data of IR, ¹H and 13C NMR. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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