| Autor: |
Masato Yoshikawa, Yuji Morine, Shinichiro Yamada, Katsuki Miyazaki, Kazunori Tokuda, Yu Saito, Yusuke Arakawa, Tetsuya Ikemoto, Satoru Imura, Mitsuo Shimada |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Annals of Gastroenterological Surgery, Vol 5, Iss 2, Pp 252-258 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2475-0328 |
| DOI: |
10.1002/ags3.12404 |
| Popis: |
Abstract Aim Diffusion‐weighted magnetic resonance imaging (DWI‐MRI) is used to predict tumor malignancy. Here we explored the role of apparent diffusion coefficient (ADC) values in the treatment of patients with resectable colorectal liver metastasis (CRLM). Methods Magnetic resonance imaging (MRI) scans were conducted using a Signa HDe or Signa Explorer 1.5‐T scanner (GE Healthcare). ADC maps were calculated using DWI with b values of 0, 20, and 800 s/mm2. We enrolled 60 patients who underwent upfront hepatic resection for CRLM and divided them into ADC‐high (n = 30) and ADC‐low (n = 30) groups. Clinicopathological variables of the groups were compared. Immunohistochemical analysis of HIF‐1α expression in tumor tissues was performed, and the relationship between the ADC value and HIF‐1α expression was evaluated. Results The disease‐free survival rate of the ADC‐low group was significantly lower than that of the ADC‐high group (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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