Comorbidity in predicting surgical outcomes for gastric cancer

Autor: V. A. Suvorov, S. I. Panin, N. V. Kovalenko, V. V. Zhavoronkova, M. P. Postolov, S. E. Tolstopyatov, A. A. Panina, Sh. R. Suleymanov, E. Sh. Vezirov, I. A. Peshkurova
Jazyk: ruština
Rok vydání: 2023
Předmět:
Zdroj: Сибирский онкологический журнал, Vol 22, Iss 4, Pp 5-13 (2023)
Druh dokumentu: article
ISSN: 1814-4861
2312-3168
DOI: 10.21294/1814-4861-2023-22-4-5-13
Popis: Objective: The present study aimed to analyze the treatment outcomes and develop a predictive model of surgical treatment for gastric cancer, taking into account the comorbidity of patients. Material and Methods. The treatment outcomes were studied in 477 (100 %) gastric cancer patients. Patients were stratifed into two groups according to the Age-Adjusted Charlson Comorbidity Index (ACCI) (0–4 points – 311 (65,2 %), more than 4 points – 166 (34,8 %) patients). Two hundred and seventy six patients (57.9 %) underwent distal or total gastrectomy, 178 (37.3 %) total gastrectomy, 19 (4 %) minimally invasive gastrectomy, and 4 (0.8 %) patients underwent extirpation of the gastric stump. The construction of models for the prognosis of surgical treatment was carried out using binary logistic regression, the comparison of models – by analyzing error curves (ROC-analysis). Results. The incidence rate of postoperative complications (grade III-V) according to the Clavien-Dindo classifcation was signifcantly higher in group 2 (9.9 %, 47/477) compared to group 1 (2.1 %, 10/477) (χ2 =64.79, p
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