Tuning the Toxicity of Reactive Oxygen Species into Advanced Tumor Therapy

Autor: An Xie, He Li, Yumei Hao, Yujia Zhang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 1556-276X
DOI: 10.1186/s11671-021-03599-8
Popis: Abstract The biological functions and toxic effects of reactive oxygen species (ROS) are generally entangled. A large amount of ROS may cause oxidative damage to cell biomolecules, leading to cell death. Tumor treatment can be carried out by using the toxicity of ROS, and various nanosystems related to ROS have been designed. In fact, the level of active oxygen in the biological microenvironment can be regulated in advanced therapeutics via designed nanoscale engineering, which can open up a new direction of treatment with specific simplicity. In this progress report, the authors first introduced how ROS causes cell death. Then, recent studies on converting the inherent toxicity from ROS into advanced treatment tools are highlighted.
Databáze: Directory of Open Access Journals