Chinese medicinal herbs for reducing endocrine therapy-induced side effects in patients with hormone receptor‐positive breast cancer: a systematic review and meta-analysis

Autor: Shaoqing Chen, Yifang Gao, Haichao Liu, Jin Jing, Zhengyu Yang, Haoming Zhu, Bairui Chen, Yu Wang, Ting Zhang, Shizhong Wang, Jianping Lin
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pharmaceutical Biology, Vol 61, Iss 1, Pp 722-736 (2023)
Druh dokumentu: article
ISSN: 13880209
1744-5116
1388-0209
DOI: 10.1080/13880209.2023.2203193
Popis: AbstractContext Chinese medicinal herbs (CMH) have been considered a potentially efficacious approach for patients with breast cancer that experience adverse effects from endocrine treatment.Objective To investigate the impact of CMH on endocrine therapy-induced side effects in patients with hormone receptor-positive (HR+) breast cancer.Methods Ten databases (e.g., PubMed, Web of Science, Cochrane Library, China National Knowledge Information Database and other databases) were searched up to 20 May 2022. The search terms included Chinese herb, breast cancer, endocrine therapy, clinical trial and their mesh terms. The study selection and data extraction were performed by two independent reviewers. The risk of bias was evaluated using the Cochrane risk of bias method.Results A total of 31 studies with 2288 patients were included. There were significant improvements in bone mineral density (BMD) [lumbar BMD (MD 0.08, 95% CI 0.07 to 0.09, p
Databáze: Directory of Open Access Journals
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