Biosensor Response at Mixed Enzyme Kinetics and External Diffusion Limitation in Case of Substrate Inhibition
| Autor: | J. Kulys |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Nonlinear Analysis, Vol 11, Iss 4 (2006) |
| Druh dokumentu: | article |
| ISSN: | 1392-5113 2335-8963 |
| DOI: | 10.15388/NA.2006.11.4.14740 |
| Popis: | The action of a biosensor containing non Michaelis-Menten enzyme was modeled at mixed enzyme kinetics and external diffusion limitation in the case of substrate inhibition. The calculations show that at the electrode surface multi steady-state concentrations of substrate may be generated if diffusion module is much larger than 1 and the substrate bulk concentration is much bigger than Michaelis-Menten parameter. The multi steady-state concentration generates multi response of the biosensor. The production of the multi steadystate may cause the biosensor response oscillation. |
| Databáze: | Directory of Open Access Journals |
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