Role of C- reactive proteins and liver function tests in assessing the severity of dengue fever

Autor: Akash Khetpal, Ansab Godil, Muhammad Tanveer Alam, Inam ul Haq Muhammad Makhdoom, Arsalan Majeed Adam, Muhammad Saad Ali Mallick, Mohammad Abubakar Abbas, Abdul Haseeb Abbas, Syed Saboor Hasan, Asim Shaikh, Hassan Ahmed, Rohan Kumar Ochani
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of the Pakistan Medical Association, Vol 71, Iss 3 (2020)
Druh dokumentu: article
ISSN: 0030-9982
DOI: 10.47391/JPMA.170
Popis: Objective: To determine whether C-reactive protein and liver function tests can serve as severity markers for dengue fever. Methods: The cross-sectional study was conducted in 2015-16 in Karachi and comprised patients with dengue fever visiting a tertiary care hospital. World Health Organisation classifications 1997 and 2009 were used to categorise patients according to clinical signs and symptoms. Receiver Operating Characteristics curve was used to determine discriminative ability and optimum cut-off value of biochemical markers. Comparisons were done through one-way analysis of variance using SPSS 17. Results: Of the 218 patients, 133(61%) were males and 85(39%) were females. The overall mean age was 35.07+15.96 years. Levels of C-reactive protein and total bilirubin were significantly higher for dengue haemorrhagic fever compared to dengue fever; dengue shock syndrome compared to dengue fever; dengue shock syndrome compared to dengue haemorrhagic fever; and dengue shock syndrome compared to dengue fever / dengue haemorrhagic fever (p
Databáze: Directory of Open Access Journals