INTERCHANGEABILITY OF MYOCARDIAL CYTOPROTECTORS IN PATIENTS WITH ISCHEMIC HEART DISEASE. DIFFICULT QUESTIONS –SIMPLE SOLUTIONS

Autor: Zh. M. Sizova
Jazyk: English<br />Russian
Rok vydání: 2015
Předmět:
Zdroj: Рациональная фармакотерапия в кардиологии, Vol 9, Iss 2, Pp 183-187 (2015)
Druh dokumentu: article
ISSN: 1819-6446
2225-3653
DOI: 10.1234/1819-6446-2013-2-183-187
Popis: Indications for myocardial cytoprotector, trimetazidine, in patients with ischemic heart disease are analyzed and justified according to evidence based medicine. Results of a multicenter randomized comparative KARDIOKANON study are discussed in terms of efficacy and tolerability of two variants of the complex 12-week treatment in patients with angina II-III functional class, based on the original and generic drugs. The study showed clinical equivalence of the generic DeprenormR (Canonpharma Production) to the original trimetazidine.
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