Evaluation of subclinical left ventricular systolic dysfunction in obese patients by global myocardial work

Autor: Jun Huang, Guang-an Li, Jing Wang, Yu-wen Jiao, Zhi-feng Qian, Li Fan, Li-ming Tang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1758-5996
DOI: 10.1186/s13098-023-01230-7
Popis: Abstract Objective To evaluate subclinical LV systolic dysfunction in obese patients by global myocardial work (MW). Methods A total of 589 obese patients and 100 normal controls were enrolled in the study. The global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), global wasted work (GWW) and global work efficiency (GWE) were generated by a noninvasive pressure-strain loop (PSL) in apical 3-, 4- and 2-chamber views acquired by two-dimensional echocardiography. All obese patients were divided into three groups: class I obesity (mild) 30–35 kg/m2, class II obesity (moderate) 35–40 kg/m2 and class III obesity (severe) > 40 kg/m2. These values were compared among the three groups. The independent influencing factors of subclinical LV systolic dysfunction in obese patients were explored by constructing a multiple regression model. ROC analysis was performed to determine the performance of MW to detect subclinical LV systolic dysfunction in obese patients. Results The absolute value of GLS in obese patients was significantly lower than that in normal controls (P
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje