Analysis on the risk factors for multiple transfusion in patients with moderate or severe traumatic brain injury

Autor: Hua-shan LU, De-chang ZHAO, Bin REN, Shun-zhong ZHAO, Zong-yuan ZHU, Da-wei ZHANG, Lian-shen FANG, Li-hong LI
Jazyk: English<br />Chinese
Rok vydání: 2020
Předmět:
Zdroj: Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 20, Iss 7, Pp 608-613 (2020)
Druh dokumentu: article
ISSN: 1672-6731
Popis: Objective To analyze the risk factors for multiple transfusions in patients with moderate or severe traumatic brain injury (TBI). Methods The clinical data of 53 patients undergoing decompressive craniectomy with moderate or severe TBI from January 2018 to June 2019 were analyzed. Coagulation indexes were tested before decompressive craniectomy. The factors associated with multiple transfusions were analyzed by univariate and multivariate Logistic regression analysis. Results Patients were divided into multiple transfusion group (11cases) and control group (42 cases, no transfusion or single transfusion). Thrombin time (P=0.041), international normalized ratio (P=0.048), fibrinogen degradation product (P=0.000) and D⁃dimer (P=0.001) in the multiple transfusion group were higher than those in the control group, while fibrinogen was lower than those in the control group (P=0.006). Logistic regression analysis showed that fibrinogen degradation product was a risk factor for multiple transfusions (OR=1.013, 95%CI:1.005-1.021; P=0.002). Conclusions Elevated fibrinogen degradation product is a risk factor for multiple transfusions in patients with moderate or severe TBI. DOI:10.3969/j.issn.1672⁃6731.2020.07.009
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