| Popis: |
Introduction: Therapeutic efficacy of Bhasma gets altered and its therapeutic arena increases with increase in the number of Puta, simultaneously increase in the number of Puta increase cost, time for manufacture. Classical texts favor sensory analysis for inprocess as well as product standard, especially for Bhasma dosage forms. The present study was carried out to develop quality control technique for the discernment of Abhraka Bhasma samples during the subsequent stages of Marana (comparison between 10, 20, 40, and 60 Puti Abhraka Bhasma) on the basis of color and touch feel through the discriminative method. Methods: Among the available sensory methods, two alternative forced choice methods were adopted. Result: The results were analyzed using the receiver operating characteristics curve, area under curve (AUC) and d-prime (d') with the help of the sensR package at R-studio ver. 1.0.143. The sample was positively marked with a P < 0.001 and an AUC of 0.866 in color and touch of 0.566, 0.600, 0.533, and 0.899. Conclusion: The critical investigation technique well differentiated against Abhraka Bhasma samples and thus could aid as economical quality control device. |
