Metformin: A Potential Treatment for Acne, Hidradenitis Suppurativa and Rosacea

Autor: Minah Cho, Yu Ri Woo, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Acta Dermato-Venereologica, Vol 103 (2023)
Druh dokumentu: article
ISSN: 0001-5555
1651-2057
DOI: 10.2340/actadv.v103.18392
Popis: Metformin is a widely used drug for treatment of diabetes mellitus, due to its safety and efficacy. In addition to its role as an antidiabetic drug, numerous beneficial effects of metformin have enabled its use in various diseases. Considering the anti-androgenic, anti-angiogenic, anti-fibrotic and antioxidant properties of metformin, it may have the potential to improve chronic inflammatory skin diseases. However, further evidence is needed to confirm the efficacy of metformin in dermatological conditions, This review focuses on exploring the therapeutic targets of metformin in acne vulgaris, hidradenitis suppurativa and rosacea, by studying their pathogeneses.
Databáze: Directory of Open Access Journals