Efficacy and safety of pulsed‐field versus conventional thermal ablation for atrial fibrillation: A systematic review and meta‐analysis

Autor: Ahmed Mazen Amin, Abubakar Nazir, Mohamed T. Abuelazm, Ahmed A. Ibrahim, Hossam Elbenawi, Aya Aboutaleb, Mohamed Ellabban, Moumen Arnaout, Mustafa Turkmani, Basel Abdelazeem, Annabelle S. Volgman
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Arrhythmia, Vol 40, Iss 5, Pp 1059-1074 (2024)
Druh dokumentu: article
ISSN: 1883-2148
1880-4276
DOI: 10.1002/joa3.13118
Popis: Abstract Background Pulsed‐field ablation (PFA) has emerged as an innovative alternative to radiofrequency (RF) and cryoablation because it selectively targets myocardial tissue. Thus, we aim to estimate the efficacy and safety of PFA versus thermal ablation for atrial fibrillation (AF) ablation. Methods A systematic review and meta‐analysis were retrieved from PubMed, WOS, SCOPUS, EMBASE, and CENTRAL through September 2023. We used RevMan V. 5.4 to pool dichotomous data using risk ratio (RR) and continuous data using mean difference (MD) with a 95% confidence interval (CI). PROSPERO ID: CRD42023480321 Results We included 17 studies with a total of 2255 patients. PFA was significantly associated with a decreased incidence of AF recurrence (RR: 0.66 with 95% CI [0.51, 0.87], p = .003). However, there was no significant difference between PFA and thermal ablation in arrhythmia recurrence (RR: 0.92 with 95% CI [0.74, 1.46], p = .42). PFA was significantly associated with decreased total procedure time (MD: −15.15 with 95% CI [−20.23, −10.07], p
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