C-reactive protein and albumin kinetics after antibiotic therapy in community-acquired bloodstream infection

Autor: Pedro Póvoa, Olav Sivertsen Garvik, Pernille Just Vinholt, Court Pedersen, Thøger Gorm Jensen, Hans Jørn Kolmos, Annmarie Touborg Lassen, Kim Oren Gradel
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 95, Iss , Pp 50-58 (2020)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2020.03.063
Popis: Objectives: We assessed C-reactive protein (CRP) and plasma albumin (PA) kinetics to evaluate community-acquired bloodstream infection (CA-BSI) patients’ 1-year outcomes. Methods: Population-based study, with CRP and PA measurements on day 1 (D1) and D4. Relative CRP variations in relation to D1 CRP value were evaluated (CRP-ratio). Patients were classified as fast response, slow response, non-response, and biphasic response. Results: A total of 935 patients were included. At D4, the CRP-ratio was lower in survivors on D365 in comparison with D4–D30 non-survivors and D30–D365 non-survivors (p
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