Impact of short‐term, repeated water fasting on the weight of mice

Autor: Zahra Mishmast, Reza Rahimzadeh Oskuee, Amirali Aryan, Kamran Ghafarzadegan, Kiarash Ghazvini
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Journal of Fasting and Health, Vol 2, Iss 2, Pp 76-79 (2014)
Druh dokumentu: article
ISSN: 2345-2587
Popis: Introduction: Caloric restriction is a strategy applied for weight loss. Water fasting is a popular way for obesity treatment. However, little is known about the impact of water fasting on weight. Therefore, this study was conducted to investigate the effect of short-term, repeated water fasting on the weight of mice. Methods: In this study, the physiological effect of short-term, repeated water fasting on the weight of female mice was evaluated. At 6 weeks of age, mice were randomly assigned to either repeated-fasting or control group (fed ad libitum). Each group consisted of twenty mice. As the fasting period started, the repeated-fasting group had access to only water; animals had free access to food and water on non-fasting days. Body weight of each group before, during, and after the fasting period was recorded. Results: Body weight of the fasting group significantly decreased, unlike the control group. However, the fasting group gained weight rapidly after being re-fed and became significantly heavier than mice in the control group (P
Databáze: Directory of Open Access Journals