Physicochemical Stability of 5 mg/mL Pediatric Prednisone Oral Suspension in Syrspend® SF PH4

Autor:	Bonnaure Anne-Claire, Bellay Romain, Rault Pauline, Lester Marie-Antoinette, Boivin Pierre-Nicolas
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	suspension formulation excipient stability hplc (hight perfomance/pressure liquid chromatography) pediatric Therapeutics. Pharmacology RM1-950 Pharmaceutical industry HD9665-9675
Zdroj:	Pharmaceutical Technology in Hospital Pharmacy, Vol 3, Iss 2, Pp 49-57 (2018)
Druh dokumentu:	article
ISSN:	2365-2411 2365-242X
DOI:	10.1515/pthp-2018-0001
Popis:	Prednisone is a corticosteroid used in several inflammatory diseases and cancers. In France, no available prednisone drinkable formulation exists. Instead, an oral syrup of prednisone with ethanol, sodium benzoate and simple syrup is produced. However, sodium benzoate can induce neonatal icterus and alcohol is not authorized for children below 3 years of age. The aim of this study was to determine the stability of 5 mg/mL prednisone oral suspension in a commercial compounding excipient: Syrspend® SF PH4.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/cbb0690b816b4885862075bfffaf73a8 Zobrazit plný text záznamu View record in DOAJ