Antidepressant Activity of Methanolic Extract of Amaranthus Spinosus

Autor:	B.S Ashok Kumar, K Lakshman, C Velmurugan, S.M Sridhar, Saran Gopisetty
Jazyk:	angličtina
Rok vydání:	2014
Předmět:	Antidepressant Activity Amaranthus Spinosus Escitalopram Imipramine Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Basic and Clinical Neuroscience, Vol 5, Iss 1, Pp 11-17 (2014)
Druh dokumentu:	article
ISSN:	2008-126X 2228-7442
Popis:	Introduction: Depressive disorder is a prevalent psychiatric disorder, which affects 21% of the world population. The presently using drugs can impose a variety of side-effects including cardiac toxicity, hypopiesia, sexual dysfunction, body weight gain, and sleep disorder. During the last decade, there is a growing interest in the therapeutic effects of natural products on mental disorders. Amaranthus spinosus was investigation for antidepressant activity. Methods: Antidepressant activity of methanolic extract of Amaranthus spinosus (MEAS) was investigated by using Forced swimming test (FST) and Tail suspension test (TST) models. Escitalopram and Imipramine were used as reference standards. Results: It has been observed from our study that both the MEAS at higher concentration showed significant (p
Databáze:	Directory of Open Access Journals
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