Factors affecting retrieval of 12 or more lymph nodes in pT1 colorectal cancers
| Autor: | Seung-Myoung Son, Chang Gok Woo, Ok-Jun Lee, Sang-Jeon Lee, Taek-Gu Lee, Ho-chang Lee |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Journal of International Medical Research, Vol 47 (2019) |
| Druh dokumentu: | article |
| ISSN: | 0300-0605 1473-2300 03000605 |
| DOI: | 10.1177/0300060519862055 |
| Popis: | Objective The aim of this study was to identify clinicopathological factors that affect the number of lymph nodes (LNs) (12 or more) retrieved from patients with colorectal cancer (CRC), particularly those with pathologic T1 (pT1) disease. Methods From 429 CRC patients, 75 pT1 cancers were identified and digitally scanned. Binary logistic regression analysis was performed to identify the clinicopathological factors affecting the number of LNs retrieved from all 429 patients and from the subset of patients with pT1 CRC. Results For the 429 patients, the mean number of harvested LNs per specimen was 20 (median, 19). The number of retrieved LNs was independently associated with maximum tumor diameter > 2.3 cm and right-sided tumor location. The mean number of LNs retrieved from the 75 patients with pT1 CRC was 14 (median, 15); retrieval of 12 or more LNs from this group was independently associated with maximum tumor diameter > 14.1 mm. Conclusion The number of LNs retrieved from patients with CRC was associated with maximum tumor diameter and right-sided tumor location. For patients with pT1 CRC, maximum tumor diameter was independently associated with the harvesting of 12 or more LNs. |
| Databáze: | Directory of Open Access Journals |
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