Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea

Autor: Maryline Beurg, Runjia Cui, Adam C. Goldring, Seham Ebrahim, Robert Fettiplace, Bechara Kachar
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-04589-8
Popis: Mechanoelectrical transduction channel (MET) current found in stereocilia of hair cells matures over the first postnatal week. Here the authors look at the contribution of transmembrane channel-like protein 1 and 2 (TMC1 and TMC2) to MET current during development of tonotopic gradients.
Databáze: Directory of Open Access Journals