Biosynthesis and characterization of nickel oxide nanoparticles by using aqueous grape extract and evaluation of their biological applications

Autor: Baraa Y. Hussein, Ahmed Mishaal Mohammed
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Results in Chemistry, Vol 3, Iss , Pp 100142- (2021)
Druh dokumentu: article
ISSN: 2211-7156
DOI: 10.1016/j.rechem.2021.100142
Popis: This study involved the use of aqueous extract from grapes as reducing substance for the green synthesis of NiO nanoparticles (NiONPs). The morphology, crystalline structure and elementary composition were investigated through various characterisation methods, such as X-ray diffraction, scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy and UV–Visible spectroscopy, to demonstrate the synthesis of pure NiONPs. Strong anti-bacterial inhibitory activities of NiONPs have been examined by pathogenic bacterial strains studied against Gram-negative bacterial strain Klebsiella pneumoniae and Gram-positive bacterial strain Staphylococcus aureus. Potential cytotoxicity against human breast cancer (MCF-7) and human brain cancer (AMGM5) cell lines was shown by NiONPs. NiONPs have shown excellent biological applications. Moreover, NiO nanoparticles exhbibit toxicity to be safely used for different biomedical applications.
Databáze: Directory of Open Access Journals