Protective effect of curcumin in fructose-induced metabolic syndrome and in streptozotocin-induced diabetes in rats

Autor:	Adriana Bulboacă, Sorana D Bolboacă, Habil Soimiţa Suciu
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	Curcumin Diabetes mellitus Fructose Metabolic syndrome Oxidative stress Streptozotocin–induced diabetes Medicine
Zdroj:	Iranian Journal of Basic Medical Sciences, Vol 19, Iss 6, Pp 585-593 (2016)
Druh dokumentu:	article
ISSN:	2008-3866 2008-3874
Popis:	Objective: The aim of this study was to investigate the effect of pre-treatment with curcumin on metabolic changes induced by two different pathophysiological mechanisms in rats (fructose diet and streptozotocin (STZ)-induced diabetes mellitus). Materials and Methods: Five groups with 10 rats per group were investigated: control group (healthy rats), fructose diet groups without any pre-treatment (FD), fructose diet groups with curcumin pre-treatment (FDC), STZ-induced diabetes mellitus without any pre-treatment (SID) and STZ-induced diabetes mellitus with curcumin pre-treatment (SIDC). Systolic blood pressure, and several metabolic and oxidative stress parameters were assessed. Results: Systolic blood pressure significantly increased in all groups compared with control group (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/bab85ac077c64c21a08f564ee9be2cd0 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF