| Autor: |
Murat Gündüz, Sefika Sakalli, Yasemin Günes, Erol Kesiktas, Dilek Özcengiz, Geylan Isik |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Journal of Anaesthesiology Clinical Pharmacology, Vol 27, Iss 2, Pp 220-224 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
0970-9185 |
| DOI: |
10.4103/0970-9185.81823 |
| Popis: |
Objective: The aim of this randomized, controlled study was to compare the sedoanalgesic effects of ketamine-dexmedetomidine and ketamine-midazolam on dressing changes of burn patients. Materials and Methods: Following Ethics Committee approval and informed patient consent, 90 ASA physical statuses I and II adult burn patients were included in the study. Patients were randomly divided into three groups. Ten minutes before dressing change, the dexmedetomidine group (group KD) ( n=30) received a continuous infusion of dexmedetomidine at a rate of 1 μg kg-1 , the midazolam group (group KM) ( n=30) received a continuous infusion of midazolam at a rate of 0.05 mg kg-1 and the saline group (group KS) ( n=30) received a continuous infusion of saline intravenously. One minute before dressing change, each patient was administered 1 mg kg-1 ketamine intravenously. Hemodynamic variables, pain and sedation scores, the number of patients requiring additional ketamine, time to dressing change and recovery time were recorded. Results: Systolic blood pressure (SBP) values were significantly lower at, before and after ketamine administration; and 5, 10 and 15 minutes after the procedure in group KD in comparison with the other groups ( P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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