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The treatment of severe and deep soft tissue infections, especially those combined with fascial necrosis is complex and involves a multidisciplinary team. The aim is to research the effect of topical application of Ozoile®, stable ozonides from organic extra-virgin olive oil +OILin the complex treatment of soft tissue infections and chronic wounds and to optimize the algorithm of these applications. Results: We applied LOT to a total of 84 patients (22.1%) of all 380 patients with soft tissue infections treated for the period March 2022-March 2023 at the First surgical clinic of Medical University – Pleven, Bulgaria. At Department “Surgical diseases” there were 49 (58,3%) patients with the superficial inflammatory process, 6 (7,1%) with chronic wounds, and 27 (34,6%) with deep soft tissue infection and necrotizing fasciitis who received topical applications of Ozoile®, stable ozonides from organic extra-virgin olive oil +OIL®OT. We compared the results with a group of 296 patients treated with conventional methods and routinely used antiseptics – hydroperoxide, povidone-iodine, and chlorhexidine gluconate. Statistically significant results in the Ozoile® group were: wound size reduction by 25% on the 5th day of treatment (p |
