In vivo hypoglycemic study of Manilkara zapota leave and seed extracts

Autor: Saikat Ranjan Paul, Md. Lukman Hakim
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Bangladesh Journal of Pharmacology, Vol 10, Iss 1 (2015)
Druh dokumentu: article
ISSN: 1991-0088
DOI: 10.3329/bjp.v10i1.21475
Popis: The hypoglycemic activity of pet-ether extracts of leaves and methanol extracts of seeds of Manilkara zapota was evaluated in the study. The oral glucose tolerance test was performed in mice treated with 2 mg/kg glucose solution and the blood glucose level was determined after 15, 30, 60, 90 and 120 min of administration. Alloxan (70 mg/kg) was injected intravenously to induce diabetes in mice. The hypoglycemic study was carried out 7 days. In glucose tolerance test all extracts achieved significant p values (p
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