Estimating the burden of pediatric HIV in an ‘A’ category district in India: an epidemiological study

Autor: Anju Sinha, Reynold Washington, Rajeev Sethumadhavan, Rajaram Subramanian Potty, Shajy Isac, Vasantha Thavraj, Ravindra Mohan Pandey
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Pediatrics, Vol 21, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 1471-2431
DOI: 10.1186/s12887-021-02836-4
Popis: Abstract Background India lacks epidemiological information on the disease burden of pediatric HIV. The National AIDS Control Program (NACP) estimates the numbers of HIV-positive children as a proportion of adult persons living with HIV. A third of HIV-positive children die before their first birthday and a half before they reach their second birthday. The early detection of HIV is crucial for the prevention of morbidities, growth delays, and death among HIV-positive children. Methods The study aimed to estimate the disease burden of pediatric HIV among children in ‘A’ category district of a high HIV prevalence state. An ‘A’ category district is defined by the presence of > 1% HIV prevalence among the general population, as estimated by HIV Sentinel Surveillance. The study used an innovative three-pronged strategy combining cross-sectional and longitudinal methods. The overall burden of pediatric HIV was calculated as a product of cases detected multiplied by a net inflation factor, for each of three strategies. Results The existing pool of HIV infection in the district is estimated to be 3266 (95% CI: 2621–4197) HIV positive children
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