Neurotrophic factors in patients with primary open-angle glaucoma and age-related cataract. Part 2. Brain-derived neurotrophic factor

Autor: A. A. Shpak, A. B. Gekht, T. A. Druzhkova, K. I. Kozlova, N. V. Gulyaeva
Jazyk: ruština
Rok vydání: 2018
Předmět:
Zdroj: Офтальмохирургия, Vol 0, Iss 4, Pp 46-51 (2018)
Druh dokumentu: article
ISSN: 0235-4160
2312-4970
DOI: 10.25276/0235-4160-2018-4-46-51
Popis: Purpose. To study the content of the brain-derived neurotrophic factor (BDNF) in the aqueous humor (AH), lacrimal fluid (LF), and blood serum (BS) in patients with primary open-angle glaucoma (POAG) and age-related cataract.Material and methods. We examined 141 people (141 eyes), of them 55 patients with POAG combined with age-related cataract, 57 patients with age-related cataract, and 29 persons without ophthalmic pathology. The content of BDNF in the AH (except healthy individuals), LF and BS was studied.Results. The levels of BDNF in LF and BS did not differ in cataract patients and healthy controls. Compared to patients with cataract the concentration of BDNF in patients with cataract and POAG was significantly reduced in the AH and LF (P
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