Features of microcirculation in school age children with chronic gastroduodenal pathology combined with arterial hypertension

Autor: T. N Mikhiejeva, D. Yu. Nechytailo
Jazyk: English<br />Russian<br />Ukrainian
Rok vydání: 2017
Předmět:
Zdroj: Zaporožskij Medicinskij Žurnal, Iss 4, Pp 400-403 (2017)
Druh dokumentu: article
ISSN: 2310-1210
2306-4145
DOI: 10.14739/2310-1210.2017.4.104873
Popis: Pathology of the digestive organs and the cardiovascular system in children takes one of the leading places among somatic diseases inUkrainein recent years. A special importance of these lesions development belongs to microcirculation disorders. Therefore, the aim of the study was to assess the state of nail bed capillaries microcirculation in schoolchildren with chronic gastroduodenitis combined with arterial hypertension. Materials and Methods. 80 school-age children residents of Chernivtsi and Chernivtsi region were observed. Among them were 40 children with various forms of chronic gastroduodenitis, who made up the main group, and 40 clinically healthy children (control group). Blood pressure measurement was provided with automatic and mechanical tonometers three times at 3 minutes intervals between each measurement. All children were examined by biomicroscopy of nail bed capillaries. Quantitative and qualitative indicators were evaluated: perivascular changes, vascular changes (in venules, arterioles and capillaries), intravascular changes (venules, arterioles and capillaries). Results and Discussion. In the 10 children from the main group concomitant hypertension was found. The level of the average systolic blood pressure among them amounted to 143.3 ± 2.72 mm Hg, and the average diastolic blood pressure was 94.0 ± 1.88 mm Hg. In children with chronic gastroduodenitis and hypertension significantly more frequently identified symptoms of microcirculation disorders: changes in the shape and the diameter of capillaries, local spasm, increased tortuosity, slowing blood flow and the presence of "sludged blood" phenomenon in the microvessels. Conclusions. The above-mentioned changes in children of the main group could be attributed to the result of autonomic dysregulation, which in turn is accompanied by violation of hemodynamics at all levels, including at the capillary.
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