| Autor: |
Sinan Kocatürk, Nurettin Özdemir, Gökhan Kuran, Ünsal Erkam, Aykut Babila |
| Jazyk: |
angličtina |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
Turkish Archives of Otorhinolaryngology, Vol 41, Iss 2, Pp 89-94 (2003) |
| Druh dokumentu: |
article |
| ISSN: |
2667-7474 |
| Popis: |
Objectives:The aims of this study were to determine the incidence of occult metastasis in patients with supraglottic cancer; to assess whether the presence of such metastases was related to extent of the primary tumor (T) and its grading (G). According to our results we discussed which therapeutic approach should be used in patients clinically classified as N0 neck.Materials and Methods:We examined 48 patients with supraglottic squamous cell carcinoma that were operated by horizontal supraglottic laryngectomy or total laryngectomy and elective bilateral neck dissection.Results:The incidence of occult lymph node metastasis in our series was 26.47%. Based on to the preoperative T staging, the incidence of occult metastasis was 14% T1 tumors, 20% T2 tumors, 40% in T3 tumors and 50% in T4 tumors. In the terms of grading, occult metastases were found in 13% of G1 tumors, 33% of G2 tumors, 42% of G3 tumors. When the effects of these factors were combined, there were 15.6% occult metastases in the cases categorized as T1-T2/G1+G2 whereas the rate was 50% in the patients with T3-T4/G3 lesions. Occult lymph node metastases were detected contralateral to primary tumor in 20% of the patients in whom tumors confined to one side. Occult lymph node metastases were detected bilaterally in 33% of patients in whom tumors reaching the midline.Conclusion:The incidence of occult lymph node metastases appears to be correlated with the values of T and degree of differentiation (G). When the effects of 2 factors combined (T1-T2/G1+G2, T3-T4/G3) the incidence reaches from 15.6% up to 50%. According to our results, bilateral neck dissection is the most rational therapeutic measure to be taken. |
| Databáze: |
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| Externí odkaz: |
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