Autor: |
Isabella eAlbanese, Stella S Daskalopoulou, Bin eYu, Zhipeng eYou, Jacques eGenest, Alawi eAlsheikh-Ali, Adel Giaid Schwertani |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
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Zdroj: |
Frontiers in Pharmacology, Vol 7 (2016) |
Druh dokumentu: |
article |
ISSN: |
1663-9812 |
DOI: |
10.3389/fphar.2016.00149 |
Popis: |
Background and aims: The aims of the present study were to determine the expression of urotensin II (UII), urotensin-II related peptide (URP) and their receptor (UT) in stable and unstable carotid atherosclerosis, and determine the effects of UII on human aortic smooth muscle cell (SMCs) calcification.Methods and Results: We examined UII, URP and UT protein expression in 88 carotid endarterectomy specimens using immunohistochemistry. Expression of UII, URP and UT was more evident in unstable compared to stable plaques (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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