| Autor: |
Luu Thi Thanh Duyen, Bui Van Manh, Tran Thi Phuong Thao, Le Van Khanh, Bui Ngoc Linh Trang, Ngo Truong Giang, Ha Van Quang, Nguyen Thanh Viet, Ngo Thu Hang, Can Van Mao, Nguyen Linh Toan, Hoang Van Tong |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Future Science OA, Vol 8, Iss 10 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2056-5623 |
| DOI: |
10.2144/fsoa-2022-0077 |
| Popis: |
Aim: The current study investigated the plasma levels of angiopoietin-1/-2 and their association with clinical outcomes of sepsis. Methods: Angiopoietin-1 and -2 levels were quantified in plasma from 105 patients with severe sepsis by ELISA. Results: Angiopoietin-2 levels elevated according to the severity of sepsis progression. Angiopoietin-2 levels were correlated with mean arterial pressure and platelets counts, total bilirubin, creatinine, procalcitonin, lactate levels and SOFA score. Angiopoietin-2 levels accurately discriminated for sepsis with an AUC = 0.97 and septic shock from severe sepsis patients (AUC = 0.778). Conclusion: Plasma angiopoietin-2 levels may serve as an additional biomarker for severe sepsis and septic shock. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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