Use of Brentuximab Vedotin in a Non-HIV Patient with Primary Effusion Lymphoma

Autor: Joana Ferra, Filipa Mousinho, Francisca Miranda, Sandra André, Celina Afonso, Fernando Nogueira
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2021)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2021_002345
Popis: Primary effusion lymphoma is a rare and aggressive large B-cell lymphoma presenting as malignant effusion with poor prognosis. Although it is more prevalent among HIV patients, it has also been described in non-HIV immunocompromised individuals. Given its rarity, there are no large randomized trials regarding the best therapeutic option. The choice of therapy is based on retrospective studies, case reports and preclinical data. We present the case of a non-HIV patient with relapsed disease after treatment with CHOP who was then successfully treated with brentuximab vedotin, achieving complete remission.
Databáze: Directory of Open Access Journals