Kidney Transplantation Confers Survival Benefit for Candidates With Pulmonary Hypertension
| Autor: | Michelle C. Nguyen, MD, MPH, Teresa Po-Yu Chiang, MD, MPH, Allan B. Massie, PhD, MHS,, Sunjae Bae, KMD, PhD, Jennifer D. Motter, MS, Daniel C. Brennan, MD, Niraj M. Desai, MD, Dorry L. Segev, MD, PhD, Jacqueline M. Garonzik-Wang, MD, PhD |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Transplantation Direct, Vol 7, Iss 8, p e738 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2373-8731 00000000 |
| DOI: | 10.1097/TXD.0000000000001191 |
| Popis: | Background. Kidney transplantation (KT) is controversial in patients with pretransplant pulmonary hypertension (PtPH). We aimed to quantify post-KT graft and patient survival as well as survival benefit in recipients with PtPH. Methods. Using UR Renal Data System (2000–2018), we studied 90 819 adult KT recipients. Delayed graft function, death-censored graft failure, and mortality were compared between recipients with and without PtPH using inverse probability weighted logistic and Cox regression. Survival benefit of KT was determined using stochastic matching and stabilized inverse probability treatment Cox regression. Results. Among 90 819 KT recipients, 2641 (2.9%) had PtPH. PtPH was associated with higher risk of delayed graft function (odds ratio, 1.23; 95% CI, 1.10-1.36; P |
| Databáze: | Directory of Open Access Journals |
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