Phylogenetic analysis of Chinese sheeppox and goatpox virus isolates

Autor: Zhou Tao, Jia Huaijie, Chen Guohua, He Xiaobing, Fang Yongxiang, Wang Xiaoxia, Guan Qisai, Zeng Shuang, Cui Qing, Jing Zhizhong
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Virology Journal, Vol 9, Iss 1, p 25 (2012)
Druh dokumentu: article
ISSN: 1743-422X
DOI: 10.1186/1743-422X-9-25
Popis: Abstract Background Sheeppox virus (SPPV) and goatpox virus (GTPV), members of the Capripoxvirus genus of the Poxviridae family are causative agents of sheep pox and goat pox respectively, which are important contagious diseases and endemic in central and northern Africa, the Middle and Far East, and the Indian sub-continent. Both sheep pox and goat pox can cause wool and hide damage, and reduce the production of mutton and milk, which may result in significant economic losses and threaten the stockbreeding. In this study, three SPPVs and two GTPVs were collected from China in 2009 and 2011. We described the sequence features and phylogenetic analysis of the P32 gene, GPCR gene and RPO30 gene of the SPPVs and GTPVs to reveal their genetic relatedness. Results Sequence and phylogenetic analysis showed that there was a close relationship among SPPV/GanS/2/2011/China, SPPV/GanS/1/2011/China and SPPV/NingX/2009/China. They were clustered on the same SPPV clade. GTPV/HuB/2009/China and GS-V1 belonged to the GTPV lineage. GS-V1 was closely related to other GTPV vaccine strains. GTPV/HuB/2009/China and GS-V1 were clustered with GTPVs from China and some southern Asian countries. Conclusion This study may expand the datum for spread trend research of Chinese SPPVs and GTPVs, meanwhile provide theoretical references to improve the preventive and control strategy.
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