PROBLEMS AND PROSPECTS OF INTERMEDIARY METABOLISM CORRECTION IN PATIENTS WITH VASCULAR COMORBIDITY

Autor:	S. A. Rumyantseva, R. G. Oganov, V. A. Stupin, E. V. Silina, A. S. Orlova, S. B. Bolevich, V. V. Afanasev, E. N. Kabaeva, S. A. Volik
Jazyk:	English<br />Russian
Rok vydání:	2015
Předmět:	vascular comorbidity myocardial infarction ischemic heart disease acute stroke fatty acids beta-oxidation beta-oxidation blockers complex cytoprotection Therapeutics. Pharmacology RM1-950 Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Рациональная фармакотерапия в кардиологии, Vol 9, Iss 3, Pp 316-322 (2015)
Druh dokumentu:	article
ISSN:	1819-6446 2225-3653
DOI:	10.20996/1819-6446-2013-9-3-316-322
Popis:	Disorders of intermediary metabolism in the glycolysis cycles and fatty acids oxidation play a major role in heart and brain lesions of vascular origin. Features of the free-radical processes in various forms of vascular disease are presented. Differences within the free-radical processes reflecting the severity of tissue energy deficit are shown in stroke patients with concomitant ischemic heart disease, atrial fibrillation, and diabetes mellitus. Various aspects of the treatment of patients with vascular comorbidity are presented with the focus on correction of intermediary metabolism disorders. Complex energy correcting therapy including beta-oxidation blocker (meldonium) is discussed.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/eba3b3189418486280d4c12981fb46f9 Zobrazit plný text záznamu View record in DOAJ