Non-canonical reader modules of BAZ1A promote recovery from DNA damage
Autor: | Mariano Oppikofer, Meredith Sagolla, Benjamin Haley, Hui-Min Zhang, Sarah K. Kummerfeld, Jawahar Sudhamsu, E. Megan Flynn, Tianyi Bai, Jennifer Zhang, Claudio Ciferri, Andrea G. Cochran |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
Druh dokumentu: | article |
ISSN: | 2041-1723 41634209 |
DOI: | 10.1038/s41467-017-00866-0 |
Popis: | ISWI chromatin remodelers regulate DNA accessibility and have been implicated in DNA damage repair. Here, the authors uncover functions, in response to DNA damage, for the bromodomain of the ISWI subunit BAZ1B and for the non-canonical PHD and bromodomain modules of the paralog BAZ1A. |
Databáze: | Directory of Open Access Journals |
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