Fabrication of Annealed Gold Nanostructures on Pre-Treated Glow-Discharge Cleaned Glasses and Their Used for Localized Surface Plasmon Resonance (LSPR) and Surface Enhanced Raman Spectroscopy (SERS) Detection of Adsorbed (Bio)molecules

Autor: Rodica Elena Ionescu, Ece Neslihan Aybeke, Eric Bourillot, Yvon Lacroute, Eric Lesniewska, Pierre-Michel Adam, Jean-Louis Bijeon
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Sensors, Vol 17, Iss 2, p 236 (2017)
Druh dokumentu: article
ISSN: 1424-8220
39075893
DOI: 10.3390/s17020236
Popis: Metallic nanoparticles are considered as active supports in the development of specific chemical or biological biosensors. Well-organized nanoparticles can be prepared either through expensive (e.g., electron beam lithography) or inexpensive (e.g., thermal synthesis) approaches where different shapes of nanoparticles are easily obtained over large solid surfaces. Herein, the authors propose a low-cost thermal synthesis of active plasmonic nanostructures on thin gold layers modified glass supports after 1 h holding on a hot plate (~350 °C). The resulted annealed nanoparticles proved a good reproducibility of localized surface plasmon resonance (LSPR) and surface enhanced Raman spectroscopy (SERS) optical responses and where used for the detection of low concentrations of two model (bio)chemical molecules, namely the human cytochrome b5 (Cyt-b5) and trans-1,2-bis(4-pyridyl)ethylene (BPE).
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