Three-dimensional assessment of coronary high-intensity plaques with T1-weighted cardiovascular magnetic resonance imaging to predict periprocedural myocardial injury after elective percutaneous coronary intervention

Autor: Hayato Hosoda, Yasuhide Asaumi, Teruo Noguchi, Yoshiaki Morita, Yu Kataoka, Fumiyuki Otsuka, Kazuhiro Nakao, Masashi Fujino, Toshiyuki Nagai, Michikazu Nakai, Kunihiro Nishimura, Atsushi Kono, Yoshiaki Komori, Tomoya Hoshi, Akira Sato, Tomohiro Kawasaki, Chisato Izumi, Kengo Kusano, Tetsuya Fukuda, Satoshi Yasuda
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Cardiovascular Magnetic Resonance, Vol 22, Iss 1, Pp 1-11 (2020)
Druh dokumentu: article
ISSN: 1532-429X
DOI: 10.1186/s12968-019-0588-6
Popis: Abstract Background Periprocedural myocardial injury (pMI) is a common complication of elective percutaneous coronary intervention (PCI) that reduces some of the beneficial effects of coronary revascularization and impacts the risk of cardiovascular events. We developed a 3-dimensional volumetric cardiovascular magnetic resonance (CMR) method to evaluate coronary high intensity plaques and investigated their association with pMI after elective PCI. Methods Between October 2012 and October 2016, 141 patients with stable coronary artery disease underwent T1-weighted CMR imaging before PCI. A conventional 2-dimensional CMR plaque-to-myocardial signal intensity ratio (2D-PMR) and the newly developed 3-dimensional integral of PMR (3Di-PMR) were measured. 3Di-PMR was determined as the sum of PMRs above a threshold of > 1.0 for voxels in a target plaque. pMI was defined as high-sensitivity cardiac troponin T > 0.07 ng/mL. Results pMI following PCI was observed in 46 patients (33%). 3Di-PMR was significantly higher in patients with pMI than those without pMI. The optimal 3Di-PMR cutoff value for predicting pMI was 51 PMR*mm3 and the area under the receiver operating characteristic curve (0.753) was significantly greater than that for 2D-PMR (0.683, P = 0.015). 3Di-PMR was positively correlated with lipid volume (r = 0.449, P
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