Serum Levels of IL-22 and ACPA in Patients with Rheumatoid Arthritis
| Autor: | Zainab A. Aldhaher, Batool Hassan Al-Ghurabi, Baydaa Hussein Alwan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Journal of Pure and Applied Microbiology, Vol 12, Iss 2, Pp 687-691 (2018) |
| Druh dokumentu: | article |
| ISSN: | 0973-7510 2581-690X |
| DOI: | 10.22207/JPAM.12.2.27 |
| Popis: | Both rheumatoid arthritis and periodontitis are complex multifactorial disorders, characterized not only by a dysfunction of basic inflammatory and tissue destructive mechanisms, but also by an altered adaptive and innate immune response in individuals. IL-22 plays an important role in inflammation, including chronic inflammatory diseases and infectious diseases. This study aimed to evaluate the serum levels of IL-22 and ACPA in RA patients. The study included 45 rheumatoid arthritis patients and 35 apparently healthy controls. Enzyme-linked immunosorbent assay (ELISA) has been used for estimation the levels of IL-22 and ACPA in serum of two studied groups. The present results revealed that mean serum levels of IL-22 and ACPA were significantly higher in patients than in healthy controls (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|