| Autor: |
Rubén Soto, Luis Antonio Díaz, Violeta Rivas, Eduardo Fuentes-López, Macarena Zalaquett, María José Bruera, Cecilia González, Gabriel Mezzano, Carlos Benítez |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Annals of Hepatology, Vol 25, Iss , Pp 100327- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1665-2681 |
| DOI: |
10.1016/j.aohep.2021.100327 |
| Popis: |
Introduction and objectives: Frailty is characterized by a poor restoration of homeostasis after a stressor event. Although it is not usually diagnosed, it has been associated with decreased survival in cirrhotic patients. We aimed to evaluate the impact of frailty and decreased gait speed over survival in cirrhotic patients at long-term follow-up. Materials and methods: We included stable cirrhotic patients Child–Pugh B-C or MELD ≥12, ≥50 years old. We performed a clinical evaluation, anthropometry, and laboratory tests. Frailty was diagnosed using Fried Frailty Index. We evaluated survival at a 4-year follow-up. Results: We included 126 patients; mean age 64 ± 8.3 years, median MELD-Na 15[12–17], median follow-up was 881 [349–1277] days. The main etiology was MAFLD (31.4%). Frailty was diagnosed in 65.1% of patients. There were no significant differences in baseline characteristics per frailty condition. Mortality was higher in frail patients than non-frail patients (68.2% versus 20.6% at 48 months, respectively; p-value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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