Non-surgical management of patients with ectopic pregnancy: A review

Autor:	Yulia E. Dobrokhotova, Tamara N. Belousova, Ekaterina I. Borovkova, Nikolai I. Sovaev, Vera D. Egorushkina, Anastasia D. Kladnitskaya, Anna Ermakova
Jazyk:	ruština
Rok vydání:	2023
Předmět:	ectopic tubal pregnancy methotrexate salpingectomy salpingostomy leucovorin trophoblast ovarian reserve Gynecology and obstetrics RG1-991
Zdroj:	Гинекология, Vol 25, Iss 4, Pp 435-441 (2023)
Druh dokumentu:	article
ISSN:	2079-5696 2079-5831 20795696
DOI:	10.26442/20795696.2023.4.202518
Popis:	An ectopic pregnancy is a medical emergency. Currently, surgery is the main method of therapy, and non-surgical management with methotrexate is considered an acceptable alternative. Methotrexate is a folic acid antagonist and has an inhibitory effect on the proliferation of trophoblast cells. There are various methotrexate regimens; the choice is based on the level of β-subunit of human chorionic gonadotropin, the location of the ectopic pregnancy and the patient's adherence to treatment. Therapy of ectopic tubal pregnancy with methotrexate is an effective and safe alternative to surgical treatment, does not affect the ovarian reserve and preserves the woman's fertility.
Databáze:	Directory of Open Access Journals
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